CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 16 enrolled
Drug / intervention
Viasys Avea Ventilator +3 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05125952
NCT05125952N/ACompleted
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Assessing Ventilator Safety in Patients on Pressure-Support Ventilation

Duke University·interventional·Posted Nov 18, 2021·Updated Oct 15, 2025

In Brief

A clinical study evaluating Viasys Avea Ventilator, Philips Respironics NM3 device, and 2 other interventions for Acute Respiratory Failure and 2 related conditions. Completed, enrolled 16 participants across 1 site.

Detailed Summary

ASOP is a prospective cohort study comparing three methods for assessing risk of self-induced lung injury in patients with acute respiratory failure being managed with pressure-support ventilation. We will describe the relationship between three different assessment methods for risk of self-induced lung injury and compare them to a gold standard measurement.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Respiratory Failure, Mechanical Ventilation Complication, Ventilator-Induced Lung Injury
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedNov 18, 2021
Enrollment StartFeb 8, 2022
Primary CompletionNov 21, 2023
Study CompletionDec 21, 2023
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 4.6 years ago

Interventions

Viasys Avea Ventilatordevice

Measuring dynamic airway driving pressure and static airway driving pressure during pressure support breath, and static airway driving pressure during a volume control breath. Measuring airway occlusion pressure during pressure support breath.

Philips Respironics NM3 devicedevice

Measuring static airway driving pressure during pressure support breath

Servo U ventilatordevice

Measuring static airway driving pressure and p0.1 during pressure support breath.

Vyaire SmartCath adult nasogastric tube with Esophageal balloondevice

Measuring static and dynamic esophageal driving pressure during pressure support breath, and esophogeal pressure change during airway occlusion maneuver.