CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 77 enrolled
Drug / intervention
Ruxolitinib cream +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05127421
NCT05127421Phase 2Completed

A Phase 2, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Facial and/or Neck Atopic Dermatitis Involvement

Incyte Corporation·interventional·Posted Nov 19, 2021·Updated Aug 15, 2024

In Brief

A Phase 2 clinical trial evaluating Ruxolitinib cream and Vehicle for Atopic Dermatitis. Completed, enrolled 77 participants across 1 site.

Detailed Summary

This is a randomized, double blind, vehicle controlled Phase 2 study with a 4-week open label extension in adolescent and adult participants with atopic dermatitis and head and/or neck involvement. It is intended to compare the efficacy and safety of ruxolitinib cream 1.5% BID versus vehicle cream, then further evaluate ruxolitinib cream as maintenance during the open label extension period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedNov 19, 2021
Enrollment StartNov 10, 2021
Primary CompletionAug 3, 2023
Study CompletionSep 29, 2023
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 4.6 years ago

Interventions

Ruxolitinib creamdrug

Ruxolitinib cream 1.5% applied twice a day (BID)"

Vehicledrug

Vehicle cream applied twice a day (BID) to affected areas