CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 166 enrolled
Drug / intervention
Daily Text Messages +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05131165
NCT05131165N/ACompleted

INcentives and ReMINDers to Improve Long-term Medication Adherence

RAND·interventional·Posted Nov 23, 2021·Updated Apr 13, 2025

In Brief

A clinical study evaluating Daily Text Messages and Incentivization based on timely ART adherence for HIV/AIDS. Completed, enrolled 166 participants across 1 site.

Detailed Summary

The study will test the feasibility and acceptability of using text messages and behavioral economics-based incentives to support anchoring Anti-Retroviral Therapy (ART) adherence to an existing routine in order to improve long-term ART medication adherence. The intervention phase of the three-phased study will constitute the pilot RCT. A sample of 150 clients who have initiated ART in the preceding three months will be randomized to either usual care (C = 50) or one of the two INMIND intervention groups (daily text message reminders with or without incentives) for three months (T1 = 50; T2=50). Subsequently, behavioral persistence will be evaluated for six months post-intervention. Assessments will be conducted at baseline, month 3, and month 9. The primary outcomes are 1) electronically measured mean medication adherence during the intervention and 2) six months post intervention, along with 3) timeliness of medication adherence during the intervention and 4) six months post-intervention.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV/AIDS
CountriesUganda

Timeline

N/ACompletedFinished
20222023202420252026
First PostedNov 23, 2021
Enrollment StartOct 25, 2021
Primary CompletionAug 23, 2023
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 4.6 years ago

Interventions

Daily Text Messagesbehavioral

Participants will receive daily text message reminders to use their routine behavior to trigger medication adherence.

Incentivization based on timely ART adherencebehavioral

Participants will be eligible to draw a prize if they take their medication within +/- one hour of the stated existing routine to which pill-taking is anchored on at least 70% of days between recruitment and the 3-month study visit.