CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 13 enrolled
Drug / intervention
Acute bout of Continuous Moderate Intensity Exercise +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05131217
NCT05131217N/ACompleted
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Effects of Acute Exercise Intensity on Cerebral Blood Flow and Cognitive Function in Older Adults

University of Virginia·interventional·Posted Nov 23, 2021·Updated Nov 29, 2023

In Brief

A clinical study evaluating Acute bout of Continuous Moderate Intensity Exercise, Acute bout of High Intensity Interval Training, and 1 other intervention for Aging Well. Completed, enrolled 13 participants across 1 site.

Detailed Summary

This study will analyze the influence of acute bout exercise intensities (continuous moderate and HIIT) on middle cerebral artery velocity (MCAv) to identify which intensity elicits the greatest increase in CBF in older adults (65+ yrs). Additionally, this study will help verify positive correlations between MCAv and cognitive function. These findings are important in determining the optimal exercise prescription for increased resilience against the age-related cognitive degradation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAging Well
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedNov 23, 2021
Enrollment StartJan 14, 2022
Primary CompletionMay 1, 2023
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 4.6 years ago

Interventions

Acute bout of Continuous Moderate Intensity Exerciseother

In this experimental intervention subjects will cycle continuously at moderate intensity (VO2 corresponding to lactate threshold) until a 200 kcal equivalent energy expenditure is reached.

Acute bout of High Intensity Interval Trainingother

In this experimental invention subjects will alternate between 1 minute of high intensity cycling (watts corresponding to 85% VO2peak) and 1 minute of low intensity cycling (watts corresponding to 35-40% VO2peak) until a 200 kcal equivalent energy expenditure is reached.

Controlother

In this intervention placebo, subjects will lay down on a flat, soft surface for 30 minutes in a dimly light room. They will not be allowed to use any electronic devices or read during this time to avoid potentially influencing continuous data recording.