CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 23 enrolled
Drug / intervention
Low-intensity Focused Ultrasounddevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05134233
NCT05134233N/ACompleted
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Investigation of Low-intensity Focused Ultrasound Parameters

Virginia Polytechnic Institute and State University·interventional·Posted Nov 24, 2021·Updated Jan 23, 2025

In Brief

A clinical study evaluating Low-intensity Focused Ultrasound for Development of LIFU for Clinical Purposes. Completed, enrolled 23 participants across 1 site.

Detailed Summary

This project examines the effects of different brain stimulation settings on muscle contractions. The investigators believe this study will help to better understand noninvasive brain stimulation techniques that may have the potential to aid in addiction, pain, and mental health issues. Participants undergo structural imaging, an fMRI and CT. These images are used to align the low-intensity focused ultrasound (LIFU) and transcranial magnetic stimulation (TMS) devices to temporarily change brain activity. Electromyography (EMG) will be used to record muscle contractions on the hand.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDevelopment of LIFU for Clinical Purposes
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedNov 24, 2021
Enrollment StartJan 14, 2022
Primary CompletionMar 11, 2024
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 4.6 years ago

Interventions

Low-intensity Focused Ultrasounddevice

LIFU application using various parameters, responses of neuromodulation recorded using TMS and EMG.