At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 10 enrolled
Drug / intervention
LOXO-305 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase 1, Open Label, Randomized, 2-Way Crossover, 3-Period Study to Evaluate the Effect of Food and a Proton Pump Inhibitor on the Pharmacokinetics of LOXO-305 in Healthy Adult Subjects
In Brief
A Phase 1 clinical trial evaluating LOXO-305 and Omeprazole for Healthy Volunteers. Completed, enrolled 10 participants across 1 site.
Detailed Summary
The main purpose of this study is to learn about how food and a PPI (omeprazole) affect LOXO-305 in healthy participants. Participation could last about nine weeks.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy Volunteers
CountriesUnited States
Collaborators--
Timeline
Phase 1CompletedFinished
2020202120222023202420252026
Enrollment StartFeb 2020
Primary CompletionMar 2020
First PostedNov 2021
TodayJul 2026
First PostedNov 24, 2021
Enrollment StartFeb 6, 2020
Primary CompletionMar 23, 2020
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 4.6 years ago
Interventions
LOXO-305drug
LOXO-305 orally.
Omeprazoledrug
Omeprazole Orally.