CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 92 enrolled
Drug / intervention
Antibiotic +3 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05141903
NCT05141903N/ACompleted

Dietary Study of a Complex Oligosaccharide With and Without a Probiotic Following Antibiotic Treatment in Healthy Volunteers

Prolacta Bioscience·observational·Posted Dec 2, 2021·Updated Feb 17, 2025

In Brief

An observational study evaluating Antibiotic, HMO Concentrate, and 2 other interventions for Healthy Adults. Completed, enrolled 92 participants across 1 site.

Detailed Summary

Complex oligosaccharides can alter the gut microbiome by aiding in the growth of certain organisms, and possibly, inhibiting others. The synergy with a probiotic may enhance gastrointestinal colonization.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy Adults
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedDec 2, 2021
Enrollment StartSep 21, 2021
Primary CompletionMay 23, 2022
Study CompletionJun 9, 2022
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 4.6 years ago

Interventions

Antibioticdietary

Vancomycin (250 mg/dose), Metronidazole (500 mg/dose)

HMO Concentratedietary

Concentrated milk fortifiers from donor human milk

Probioticdietary

B. infantis

Food Supplementdietary

Synthetic powder containing 2'-fucosyllactose (2'-FL) and lactoneotetraose (LNnT)