CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 50 enrolled
Drug / intervention
Percutaneous coronary intervention +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05142215
NCT05142215N/ACompleted
CompareCT.gov

ORBITA-CTO Pilot: A Comparison of the Impact of CTO PCI Versus Placebo on Angina in Patients With Background Optimal Medical Therapy - a Pilot Study

Mid and South Essex NHS Foundation Trust·interventional·Posted Dec 2, 2021·Updated Nov 20, 2025

In Brief

A clinical study evaluating Percutaneous coronary intervention and Placebo percutaneous coronary intervention for Stable Angina and Chronic Total Occlusion of Coronary Artery. Completed, enrolled 50 participants across 3 sites.

Detailed Summary

ORBITA-CTO Pilot is a double blinded randomised placebo-controlled trial comparing the effects of chronic total occlusion percutaneous coronary intervention versus placebo on symptoms of angina in patients with background optimal medical therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsStable Angina, Chronic Total Occlusion of Coronary Artery
CountriesUnited Kingdom
CollaboratorsImperial College London

Timeline

N/ACompletedFinished
20222023202420252026
First PostedDec 2, 2021
Enrollment StartOct 19, 2021
Primary CompletionOct 21, 2025
TodayJul 2, 2026
Enrollment to primary: 4.0 yearsPosted 4.6 years ago

Interventions

Percutaneous coronary interventionprocedure

Percutaneous coronary intervention using drug eluting stents and contemporary CTO PCI techniques on background of optimal medical therapy.

Placebo percutaneous coronary interventionprocedure

Placebo percutaneous coronary intervention procedure on background of optimal medical therapy.