CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 134 enrolled
Drug / intervention
Coronary artery bypass grafting +3 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05143671
NCT05143671N/ACompleted
CompareCT.gov

Prospective Evaluation for Hybrid Cardiac Procedures

Fondazione Policlinico Universitario Agostino Gemelli IRCCS·observational·Posted Dec 3, 2021·Updated Aug 14, 2025

In Brief

An observational study evaluating Coronary artery bypass grafting, Percutaneous coronary intervention, and 2 other interventions for Left Main Coronary Artery Disease and 7 related conditions. Completed, enrolled 134 participants across 1 site.

Detailed Summary

Multidisciplinary team-approach in order to offer personalized treatments represents the emerging mainstream in cardiovascular medicine. "Hybrid operative rooms" allow to offer selected heart-disease patients truly "tailored" operations. This study wants to evaluate the effectiveness and safety of Hybrid Procedures in cardiac patients in three subgroups of patients: * Hybrid coronary revascularization strategy (coronary by-pass + PCI); * Hybrid valve and coronary disease correction (combination of surgical valve replacement and PCI); * Hybrid coronary and carotid artery disease treatment (combination of coronary by-pass and carotid stenting). The investigators hypothesize that morbidity might be reduced by 50% in hybrid procedures group as compared with predicted Society of Thoracic Surgery (STS) score.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsLeft Main Coronary Artery Disease, Left Anterior Descending Coronary Artery Stenosis, Valve Disease, Heart, Carotid Stenosis, Coronary Artery Disease, Heart Diseases, Heart Valve Diseases, Carotid Occlusion
CountriesItaly
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedDec 3, 2021
Enrollment StartMay 13, 2021
Primary CompletionJul 30, 2025
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 4.6 years ago

Interventions

Coronary artery bypass graftingprocedure

Coronary artery bypass grafting in coronary revascularization.

Percutaneous coronary interventionprocedure

Percutaneous coronary intervention in coronary revascularization.

Surgical valve replacementprocedure

Surgical mitral and / or aortic valve replacement.

Carotid artery stentingprocedure

Carotid artery stenting.