CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 33 enrolled
Drug / intervention
Patient-controlled analgesia (PCA) +1 moredrug
Likely dose
Patient-controlled analgesia (PCA) 650 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05144828
NCT05144828Phase 4Completed
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Efficacy of Intercostal CryoAnalgesia in Patients Undergoing Robot Assisted Anatomic Lung Resection

Medical College of Wisconsin·interventional·Posted Dec 3, 2021·Updated Apr 15, 2026

In Brief

A Phase 4 clinical trial evaluating Intercostal Nerve Cryoablation and Patient-controlled analgesia (PCA) for Pain, Postoperative and Lung Diseases. Completed, enrolled 33 participants across 1 site.

Detailed Summary

This is a single center, single surgeon, prospective, randomized trial examining the addition of Cryo Nerve Block during robot assisted thoracoscopic anatomic lung resection surgery

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Postoperative, Lung Diseases
CountriesUnited States
CollaboratorsAtriCure, Inc.

Timeline

Phase 4CompletedFinished
20222023202420252026
First PostedDec 3, 2021
Enrollment StartFeb 15, 2022
Primary CompletionOct 4, 2024
Study CompletionDec 31, 2024
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 4.6 years ago

Interventions

Intercostal Nerve Cryoablationdevice

Patients will receive intraoperative intercostal nerve cryoablation using CryoICE® CRYOS-L cryoablation probes (AtriCure, Inc) to intercostal spaces 4th to 10th in thoracoabdominal aortic repairs and 4th to 8th in descending thoracic aortic repair cases prior to wound closure.

Patient-controlled analgesia (PCA)drug

Patients will have access to the standard PCA (patient-controlled analgesia) offered at Froedtert Hospital. This includes tylenol 650 mg oral, robaxin 500 mg oral, and tramadol 25-50 mg oral. All patients will have the first two ports placed at which time an intercostal nerve block of nerves 4-9 will be performed using 0.5% Marcaine with Epinephrine.