CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 70 enrolled
Drug / intervention
Curcumin mouthwash +1 moredrug
Likely dose
Curcumin mouthwash 10 mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05147376
NCT05147376Early Ph 1Completed
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Effectiveness of a Curcumin Mouthwash in Preventing Traumatic Ulcers in Patients With Fixed Orthodontic Appliances: a Randomized Clinical Trial

Chulalongkorn University·interventional·Posted Dec 7, 2021·Updated Sep 21, 2023

In Brief

A Early Phase 1 clinical trial evaluating Curcumin mouthwash and Placebo mouthwash for Oral Ulcer and Orthodontic Appliances, Fixed. Completed, enrolled 70 participants across 1 site.

Detailed Summary

The study is a randomized controlled trial. The participants will be equally allocated into 2 groups to compare clinical effectiveness of curcumin mouthwash in fixed orthodontic patients during the first month of treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOral Ulcer, Orthodontic Appliances, Fixed
CountriesThailand
Collaborators--

Timeline

Early Ph 1CompletedFinished
20222023202420252026
First PostedDec 7, 2021
Enrollment StartFeb 21, 2022
Primary CompletionAug 7, 2023
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 4.6 years ago

Interventions

Curcumin mouthwashdrug

Rinse with 10 ml for 1 minute, twice a day for 28 days after brushing in the morning and at night, following proper oral hygiene and avoid taking any liquid or food for 30 minutes after rinsing.

Placebo mouthwashdrug

Rinse with 10 ml for 1 minute, twice a day for 28 days after brushing in the morning and at night, following proper oral hygiene and avoid taking any liquid or food for 30 minutes after rinsing.