CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 176 enrolled
Drug / intervention
EN3835 +1 morebiological
Likely dose
EN3835 8mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05152173
NCT05152173Phase 2Completed

Phase 2, Double-blind, Randomized, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of EN3835 vs Placebo in the Treatment of Plantar Fibromatosis

Endo Pharmaceuticals·interventional·Posted Dec 9, 2021·Updated Mar 27, 2026

In Brief

A Phase 2 clinical trial evaluating EN3835 and Placebo for Plantar Fibromatosis. Completed, enrolled 176 participants across 43 sites.

Detailed Summary

This randomized, double-blind, placebo-controlled study will evaluate the efficacy and safety of up to 2 treatments of EN3835 vs placebo in participants with plantar fibromatosis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedDec 9, 2021
Enrollment StartNov 29, 2021
Primary CompletionJan 10, 2023
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 4.6 years ago

Interventions

EN3835biological

Participant will receive a maximum dose of up to1.8mg of EN3835 injection

Placeboother

Participant will receive a matched Placebo injection