CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 96 enrolled
Drug / intervention
Active-tDCS priming MCE +3 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05156242
NCT05156242N/ACompleted

Corticospinal and Motor Behavior Responses After 6-week Transcranial Direct Current Stimulation and Neuromuscular Electrical Stimulation Combined With Motor Control Exercises in Patients With Chronic Low Back Pain

Mahidol University·interventional·Posted Dec 14, 2021·Updated May 9, 2025

In Brief

A clinical study evaluating Active-tDCS priming MCE, Sham-tDCS priming MCE, and 2 other interventions for Low Back Pain. Completed, enrolled 96 participants across 1 site.

Detailed Summary

This study aims to 1) determine the immediate effects of transcranial direct current stimulation (tDCS) on corticospinal excitability, lumbar multifidus muscle (LM) activation, as well as lumbar stability in patients with chronic low back pain (CLBP), 2) determine the immediate effects of neuromuscular electrical stimulation (NMES) on corticospinal excitability, LM activation, as well as lumbar stability in patients with CLBP, 3) compare the effectiveness of 6-week intervention program among tDCS priming with motor control exercise (MCE), NMES priming with MCE, and MCE alone in patients with CLBP, and 4) determine the associations among corticospinal excitability, LM activation, lumbar stability, movement patterns, and clinical outcomes in patients with CLBP.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLow Back Pain
CountriesThailand

Timeline

N/ACompletedFinished
20222023202420252026
First PostedDec 14, 2021
Enrollment StartSep 3, 2021
Primary CompletionOct 31, 2024
Study CompletionDec 31, 2024
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 4.5 years ago

Interventions

Active-tDCS priming MCEdevice

tDCS is used to enhance cortical excitability before motor control exercises.

Sham-tDCS priming MCEdevice

tDCS will be set at 0 mA for 20 minutes before motor control exercise.

NMES priming MCEdevice

NMES is used to enhance lumbar multifidus motor unit recruitment before motor control exercise.

Conventional physical therapyother

Conventional physical therapy includes modality for pain control, general exercise to improve muscle strength, endurance, and flexibility, and functional training (sit to stand, walking, etc.).