At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 60 enrolled
Drug / intervention
Doxycycline 100 mg Oral Tablet +1 moredrug
Likely dose
Doxycycline 100 mg Oral Tabletfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Role of Doxycycline in the Management of Patients With Chronic Rhinosinusitis With Nasal Polyps
In Brief
A Phase 3 clinical trial evaluating Doxycycline 100 mg Oral Tablet and Prednisolone 20 mg for Nasal Polyps and Chronic Rhinosinusitis With Nasal Polyps. Completed, enrolled 60 participants across 1 site.
Detailed Summary
To evaluate the efficacy of Doxycycline as an adjunct to systemic steroids in the treatment of chronic rhinosinusitis with nasal polyps
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesEgypt
Collaborators--
Timeline
Phase 3CompletedFinished
20222023202420252026
Enrollment StartJul 2021
First PostedDec 2021
Primary CompletionSep 2023
Study CompletionJan 2024
TodayJul 2026
First PostedDec 15, 2021
Enrollment StartJul 1, 2021
Primary CompletionSep 1, 2023
Study CompletionJan 1, 2024
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 4.5 years ago
Interventions
Doxycycline 100 mg Oral Tabletdrug
Oral Doxycycline will be added to prednisolone as a comparison to using prednisolone as a sole therapy for the treatment of nasal polyps associated with chronic rhinosinusitis
Prednisolone 20 mgdrug
Prednisolone will be used in both arms as a sole therapy in one and together with doxycycline in the other