CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 34 enrolled
Drug / intervention
PF-07081532 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05158244
NCT05158244Phase 1Completed

A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO-CONTROLLED STUDY TO ASSESS THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF MULTIPLE ORAL DOSES OF PF-07081532 IN ADULT PARTICIPANTS WITH TYPE 2 DIABETES MELLITUS

Pfizer·interventional·Posted Dec 15, 2021·Updated Aug 12, 2024

In Brief

A Phase 1 clinical trial evaluating PF-07081532 and Placebo for Type 2 Diabetes Mellitus. Completed, enrolled 34 participants across 1 site.

Detailed Summary

This is a Phase 1, randomized, placebo-controlled, double-blind (investigator- and participant-blinded), sponsor-open study of PF-07081532. Study participants will receive the investigational product or placebo every day for 42 days. The purpose of the study is to evaluate the safety, tolerability and pharmacokinetics (PK) of multiple oral doses of PF-07081532 in participants with inadequately controlled type 2 diabetes mellitus, on metformin and optionally in non-diabetic participants with obesity.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
20222023202420252026
First PostedDec 15, 2021
Enrollment StartDec 22, 2021
Primary CompletionJun 15, 2022
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 4.5 years ago

Interventions

PF-07081532drug

Study Drug, once daily for 42 days

Placebodrug

Placebo, once daily for 42 days