CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 61 enrolled
Drug / intervention
User-Led Meaningful Activity Planbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05159869
NCT05159869N/ACompleted

Meaningful Activity Intervention for Individuals With Early-Stage Dementia: Involving the End User in Intervention Design

Johns Hopkins University·interventional·Posted Dec 16, 2021·Updated Jan 12, 2026

In Brief

A clinical study evaluating User-Led Meaningful Activity Plan for Dementia. Completed, enrolled 61 participants across 1 site.

Detailed Summary

Neuropsychiatric symptoms are the most difficult, distressing, and burdensome aspects of dementia care and a catalyst for long-term care placement. Intervention studies have largely focused on helping caregivers manage these symptoms. However, little has been done with regard to persons at the earliest stages of dementia, nor have persons with dementia played a direct and active, central role in helping to design intervention studies. This study focuses on building, pilot testing, and evaluating a tailored activity plan developed with persons with early-stage dementia. The goal of the intervention is to provide persons at this early stage meaningful activities and a plan for adaptation with disease progression.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDementia
CountriesUnited States

Timeline

N/ACompletedFinished
20222023202420252026
First PostedDec 16, 2021
Enrollment StartJan 24, 2022
Primary CompletionJun 21, 2024
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 4.5 years ago

Interventions

User-Led Meaningful Activity Planbehavioral

The User-Led Meaningful Activity Plan integrates persons with dementia as partners in the co-construction of an intervention involving personally meaningful activity. Activities are graded to correspond with disease progression. For example, (1) an individual who is/was a researcher may continue to maintain a job, conduct research, and even publish papers in the early stages of dementia. (2) As the dementia progresses, he or she may be able to continue to run analyses and read/access literature in his or her field. (3) In the moderate stages of dementia, this participant may read his or her existing publications or go to museums showcasing research of interest. As the disease approaches the severe stage, the participant may read very basic books about his or her former profession. (4) In the severe stages of dementia, this study participant may watch videos related to the former profession, e.g., British Broadcasting Corporation (BBC) or National Geographic.