At a glance
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Intravenous Magnesium: Prompt Use for Asthma in Children Treated in the Emergency Department
In Brief
A Phase 2 clinical trial evaluating Magnesium Sulfate, Heptahydrate and 0.9% saline for Asthma. Completed, enrolled 52 participants across 3 sites.
Detailed Summary
Many children currently being hospitalized with severe asthma could potentially avoid hospitalization and be sent home if their treatment in the emergency department was more effective. The investigators will conduct a pilot trial that will lead to a larger study to conclusively answer whether a simple and inexpensive medicine, intravenous magnesium sulfate, can be used in the emergency department to prevent hospitalization for these children.
Study Details
Timeline
Interventions
A single dose of intravenous magnesium sulfate given over 20 minutes through a peripheral intravenous line. Two arms of the study will deliver intravenous magnesium, one at a dose of 50 mg/kg, and the other at a dose of 75 mg/kg.
A single dose of intravenous 0.9% sodium chloride given over 20 minutes through a peripheral intravenous line as the placebo arm of the study.