CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 176 enrolled
Drug / intervention
Apremilast +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05174065
NCT05174065Phase 3Completed

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Apremilast (AMG 407) in Japanese Subjects With Palmoplantar Pustulosis (PPP)

Amgen·interventional·Posted Dec 30, 2021·Updated Apr 9, 2025

In Brief

A Phase 3 clinical trial evaluating Apremilast and Placebo for Palmoplantar Pustulosis. Completed, enrolled 176 participants across 40 sites.

Detailed Summary

The primary objective of the study is to evaluate the efficacy of apremilast (AMG 407) twice daily (BID) compared with placebo in participants with Palmoplantar Pustulosis (PPP).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesJapan
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedDec 30, 2021
Enrollment StartMar 8, 2022
Primary CompletionAug 19, 2023
Study CompletionJun 1, 2024
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 4.5 years ago

Interventions

Apremilastdrug

Oral tablets

Placebodrug

Oral tablets