CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 49 enrolled / 49 target
Drug / intervention
Pilot study of algorithms implementation packagebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05182606
NCT05182606N/ACompletedOn Track (0.9/mo)Completion was 33mo ago
CompareCT.gov

Consensus-based Algorithms to Address Opioid Misuse Behaviors Among Individuals Prescribed Long-term Opioid Therapy: Developing Implementation Strategies and Pilot Testing

University of Pittsburgh·interventional·Posted Jan 10, 2022·Updated Jun 30, 2026

In Brief

A clinical study evaluating Pilot study of algorithms implementation package for Opioid Misuse and Chronic Pain. Completed, enrolled 49 participants across 1 site.

Detailed Summary

The NIH Helping to End Addiction Long-term (HEAL) initiative has identified a critical next step to addressing the opioid crisis: improving treatments for opioid misuse behaviors (e.g., using more opioids than prescribed, illicit substance use) in patients prescribed long-term opioid therapy for chronic pain. In previous work, the investigators have developed innovative consensus-based algorithms to manage these behaviors. By developing implementation strategies for these algorithms, this project is directly responsive to the HEAL initiative and promises to reduce opioid misuse-related harms.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOpioid Misuse, Chronic Pain
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)

Timeline

N/ACompletedFinished
20222023202420252026
First PostedJan 10, 2022
Enrollment StartMar 1, 2022
Primary CompletionSep 30, 2023
Study CompletionSep 30, 2024
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 4.5 years ago

Arms & Interventions

Implementation Bundleexperimental

The 'Implementation Bundle' was integrated into all three participating clinics over six to nine months.

Behavioral: Pilot study of algorithms implementation package

Interventions

Pilot study of algorithms implementation packagebehavioral

The algorithm implementation package includes a link to the algorithms in the Electronic Health Record, Smartphrases, audited feedback, and instructions.