CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 13 enrolled
Drug / intervention
Working Memory Training + Behavioral Interventionbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05210608
NCT05210608N/ACompleted

Remember to Abstain: Assessment of Working Memory Training on Delay Discounting in Low-SES Cigarette Smokers

University of Kansas Medical Center·interventional·Posted Jan 27, 2022·Updated Feb 24, 2025

In Brief

A clinical study evaluating Working Memory Training + Behavioral Intervention for Tobacco Use Disorder/Cigarette Smoking. Completed, enrolled 13 participants across 1 site.

Detailed Summary

Despite widespread awareness of significant negative health consequences, cigarette smoking remains the leading cause of preventable morbidity and mortality in the US (Creamer et al., 2019; Jamal, 2018). Moreover, the highest rate of smoking and heaviest burden of smoking-related illness occurs among low-socioeconomic status (SES) individuals relative to higher SES groups (Businelle et al., 2010; Clegg et al., 2009). Low SES individuals are also 40% less likely to succeed in quitting smoking when they attempt to do so (National Center for Chronic Disease Prevention and Health Promotion (US) Office on Smoking and Health, 2014). One potential explanation for the disparity in rate of smoking and successful quit attempts may be differences in individual rates of delay discounting (DD), i.e., the degree to which rewards loses their value as the delays to their receipt increase (Odum, 2011). A proposed way to reduce steep DD and, potentially, substance use has been computer training for working memory, which has shown favorable results in a sample of individuals with stimulant dependence (Bickel et al., 2011) and substance use broadly (Felton et al., 2019), with the latter even showing decreases in cigarette smoking in a subset of the sample.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20222023202420252026
First PostedJan 27, 2022
Enrollment StartNov 30, 2021
Primary CompletionJun 30, 2022
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 4.4 years ago

Interventions

Working Memory Training + Behavioral Interventionbehavioral

Participants will be randomized to complete 10 sessions of a Working Memory Training. All participants will receive behavioral activation (a behavioral intervention for smoking cessation) and nicotine patches.