CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 44 enrolled
Drug / intervention
Low Added Sugar Diet +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05211726
NCT05211726N/ACompleted
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The Effects of Added Sugar Intake on Brain Blood Flow and Hippocampal Function in Midlife Adults

University of Delaware·interventional·Posted Jan 27, 2022·Updated Jun 12, 2025

In Brief

A clinical study evaluating Low Added Sugar Diet and High Added Sugar Diet for Aging and Healthy Diet. Completed, enrolled 44 participants across 1 site.

Detailed Summary

This study will focus on improving brain health through dietary modification of added sugars in middle aged adults (50- 64 years old). Participants will be fed two 10-day diets (one diet containing 5% of total energy from added sugars and one diet containing 25% of total energy from added sugars) and examine blood vessel function, hippocampus structure using a MRI, and memory performance.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAging, Healthy Diet
CountriesUnited States
CollaboratorsNational Institute of General Medical Sciences (NIGMS)

Timeline

N/ACompletedFinished
20222023202420252026
First PostedJan 27, 2022
Enrollment StartJan 11, 2022
Primary CompletionMay 3, 2024
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 4.4 years ago

Interventions

Low Added Sugar Dietother

Consumption of 10 days of a diet low in added sugars (5% of total caloric intake)

High Added Sugar Dietother

Consumption of 10 days of a diet high in added sugars (25% of total caloric intake)