CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 101 enrolled
Drug / intervention
Vatiquinonedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05218655
NCT05218655Phase 3Completed

An Open-Label, Safety Study for Previously Treated Vatiquinone (PTC743) Subjects With Inherited Mitochondrial Disease

PTC Therapeutics·interventional·Posted Feb 1, 2022·Updated Dec 22, 2025

In Brief

A Phase 3 clinical trial evaluating Vatiquinone for Inherited Mitochondrial Disease. Completed, enrolled 101 participants across 26 sites in 7 countries.

Detailed Summary

The primary objective of this study is to assess the safety of vatiquinone in participants with inherited mitochondrial disease who had prior exposure to vatiquinone in a PTC/BioElectron sponsored (previously Edison) clinical study or treatment plan. The study will continue until vatiquinone becomes commercially available or the program is terminated.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFrance, Italy, Japan, Poland, Spain, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedFeb 1, 2022
Enrollment StartJun 22, 2022
Primary CompletionApr 15, 2025
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 4.4 years ago

Interventions

Vatiquinonedrug

Vatiquinone will be administered per dose and schedule specified in the arm description.