CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 288 enrolled
Drug / intervention
HZ/su +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05219253
NCT05219253Phase 3Completed

A Phase 3, Randomised, Observer-blind, Placebo-controlled, Multi-centre Study to Evaluate the Immune Response and Safety of the Herpes Zoster Subunit Vaccine When Administered Intramuscularly on a 2-dose Schedule in Adults Aged 50 Years and Older in India

GlaxoSmithKline·interventional·Posted Feb 2, 2022·Updated May 15, 2025

In Brief

A Phase 3 clinical trial evaluating HZ/su and Placebo for Herpes Zoster. Completed, enrolled 288 participants across 9 sites.

Detailed Summary

The purpose of this study was to evaluate the humoral immunogenicity and safety of 2 doses of GSK Biologicals' Herpes Zoster subunit vaccine (HZ/su) administered for the prevention of Herpes Zoster (HZ) in adults aged 50 years of age (YOA) or older from India.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHerpes Zoster
CountriesIndia
Collaborators--

Timeline

Phase 3CompletedFinished
20222023202420252026
First PostedFeb 2, 2022
Enrollment StartFeb 2, 2022
Primary CompletionOct 11, 2022
Study CompletionDec 12, 2022
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 4.4 years ago

Interventions

HZ/subiological

Two doses of the HZ/su vaccine administered intramuscularly, one each at Day 1 and Month 2.

Placebodrug

Two doses of Placebo (lyophilised sucrose reconstituted with saline \[NaCl\] solution) administered intramuscularly, one each at Day 1 and Month 2.