CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 98 enrolled
Drug / intervention
Clopidogrel +2 moredrug
Likely dose
Clopidogrel 75 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05223335
NCT05223335Phase 4Completed

Clopidogrel Monotherapy in High Bleeding Risk Patients Undergoing Percutaneous Coronary Interventions: A Safety Assessment, Pilot Study to Reduce Post-Discharge Bleeding

Mayo Clinic·interventional·Posted Feb 3, 2022·Updated Feb 21, 2024

In Brief

A Phase 4 clinical trial evaluating Clopidogrel, Prasugrel, and 1 other intervention for Bleeding Complications. Completed, enrolled 98 participants across 1 site.

Detailed Summary

The goal of this research is to show that a shorter duration of two antiplatelet medications (compared to the standard of care) is safe and effective while reducing the risk of bleeding complications. Bleeding complications can cause significant problems (hospitalizations, need for blood transfusions, and even death) for patients on antiplatelet medications after coronary stents. Researchers hope to show that reducing the time on two antiplatelet agents in patients at high risk for these bleeding complications will reduce the number of bleeding events while not causing any increase in cardiovascular complications (heart attack, stent malfunction, death).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20222023202420252026
First PostedFeb 3, 2022
Enrollment StartMar 29, 2022
Primary CompletionMar 16, 2023
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 4.4 years ago

Interventions

Clopidogreldrug

75 mg/day

Prasugreldrug

60 mg bolus then 10 mg daily

Tricagrelordrug

180 mg bolus then 90 mg twice daily