CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 54 enrolled
Drug / intervention
ARGX-117 +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05225675
NCT05225675Phase 2Completed

A Phase 2, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group, Multicenter Trial to Evaluate the Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of 2 Dose Regimens of ARGX-117 in Adults With Multifocal Motor Neuropathy

argenx·interventional·Posted Feb 4, 2022·Updated May 8, 2026

In Brief

A Phase 2 clinical trial evaluating ARGX-117 and Placebo for Multifocal Motor Neuropathy. Completed, enrolled 54 participants across 40 sites in 11 countries.

Detailed Summary

This is a phase 2, randomized, double-blinded, placebo-controlled, parallel-group, multicenter trial to evaluate the safety and efficacy of 2 dose regimens of ARGX-117 versus placebo, in participants with MMN previously stabilized with IVIg (intravenous immunoglobulin).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustria, Belgium, Canada, France, Germany, Italy, Netherlands, Poland, Spain, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedFeb 4, 2022
Enrollment StartMar 31, 2022
Primary CompletionJun 4, 2024
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 4.4 years ago

Interventions

ARGX-117biological

Intravenous administration of ARGX-117

Placeboother

Intravenous administration of placebo