CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 23 enrolled
Drug / intervention
Low-oxalate controlled diet +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05229952
NCT05229952N/ACompleted
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Assessment of Endogenous Oxalate Synthesis

University of Alabama at Birmingham·interventional·Posted Feb 8, 2022·Updated May 13, 2025

In Brief

A clinical study evaluating Low-oxalate controlled diet and Primed, continuous intravenous infusion of 13C2-oxalate for Healthy and 2 related conditions. Completed, enrolled 23 participants across 1 site.

Detailed Summary

This study aims to determine the daily rate of endogenous synthesis of oxalate using carbon 13 oxalate isotope tracer technique and a low-oxalate controlled diet.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy, Kidney Stone, Obesity
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20222023202420252026
First PostedFeb 8, 2022
Enrollment StartFeb 10, 2022
Primary CompletionSep 9, 2024
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 4.4 years ago

Interventions

Low-oxalate controlled dietdietary

Participants will consume a diet that is controlled in its contents of protein, carbohydrates, fat, calcium, oxalate, vitamin C and sodium for 5 days. Participants will be asked not to take any dietary supplements, exercise strenuously, or consume food or drink that is not provided to them.

Primed, continuous intravenous infusion of 13C2-oxalateother

Participants will receive a continuous intravenous administration of carbon-13 oxalate, a naturally occurring form of oxalate, over the course of several hours until steady-state is achieved, using an IV catheter, while remaining fasting.