CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 544 enrolled / 544 target
Drug / intervention
A couples-focused intervention for HIV prevention and care in South Africabehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05231707
NCT05231707N/ACompletedHigh Momentum (10.9/mo)Completion was 6mo ago

A Couples-focused Intervention for HIV Prevention and Care in South Africa

University of Michigan·interventional·Posted Feb 9, 2022·Updated Jun 8, 2026

In Brief

A clinical study evaluating A couples-focused intervention for HIV prevention and care in South Africa for Human Immunodeficiency Virus. Completed, enrolled 544 participants across 1 site.

Signals

Enrolling ahead of pace

Detailed Summary

From a sample of 272 male-female couples (544 individuals, 272 men and 272 women) recruited from rural KaZulu-Natal, South Africa, couples will be randomized to receive either individual a package of dyadic counseling and testing (intervention arm) or an attention matched control. The research examines the impact of a package of dyadic counseling and testing on viral suppression and engagement in HIV care among sero-discordant and concordant positive male-female couples in KwaZulu-Natal, South Africa.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSouth Africa

Timeline

N/ACompletedFinished
20222023202420252026
First PostedFeb 9, 2022
Enrollment StartApr 29, 2022
Primary CompletionDec 31, 2025
Study CompletionMay 1, 2026
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 4.4 years ago

Arms & Interventions

Interventionexperimental

For couples who are prevalent sero-discordant, this will be a CHTC session. For couples who are prevalent concordant HIV-positive, the first visit will be the first Partner Steps session. For couples in which one or both do not know their sero-status or have not tested for HIV in the past 12 months, the first session will be a CHTC session.

Behavioral: A couples-focused intervention for HIV prevention and care in South Africa
Attention Matched Controlactive_comparator

Participants in the control group will receive an intervention, with the same number of sessions as couples of the same sero-status in the intervention condition, delivered via one-on-one couples counseling sessions (i.e., one couple with one counselor).

Behavioral: A couples-focused intervention for HIV prevention and care in South Africa

Interventions

A couples-focused intervention for HIV prevention and care in South Africabehavioral

From a sample of 272 male-female couples (544 individuals, 272 men and 272 women) recruited from rural KaZulu-Natal, South Africa, couples will be randomized to receive either individual a package of dyadic counseling and testing (intervention arm) or an attention matched control.