At a glance
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Prevention and Screening Intervention Project - Towards Elimination of Cervical Cancer
In Brief
A clinical study evaluating Community mobilisation for hrHPV self-testing, hrHPV self-testing, and 4 other interventions for HPV Infection and 2 related conditions. Completed, enrolled 30,000 participants across 1 site.
Detailed Summary
The research project applies the protocol of the World Health Organisation for screening of cervical cancer, with testing of hrHPV as first screening, followed by Visual Inspection of the cervix with Acetic Acid for hrHPV-positive women and for women with minor lesions thermo-ablation of affected areas. This procedure is applied in Uganda, India and Bangladesh. In Slovakia hrHPV-positive women are offered Pap-smear and for women with Pap IV lis excision.
Study Details
Timeline
Interventions
use of social media, written media, theatre and other sources of communication to reach women, and relatives, to convince them of importance of screening.
use of swabs that women insert in the vagina for taking sufficient material for testing for hrHPV. For women who are not confident to perform this this nurses provide assistance.
based on the results of the test, follow-up is offered. In case of hrHPV negative test, retesting after five years. In case of hrHPV positive test, VIA in a nearby clinic. Women have to be motivated to adhere to follow-up
Test offers insight into existence of dysplasia of the cervix by colouring the transition area
Women with identified dysplasia lesions are offered immediate therapy to remove the infected superficial surface of the cervix
Cytology for identification of abnormal cells in the cervix, and classification of stages of dysplasia or pre-cancerous lesions