CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 40 enrolled
Drug / intervention
Mouth rinsedrug
Likely dose
Mouth rinse 10 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05239598
NCT05239598Phase 2Completed

A Phase II, Randomized Trial to Test the Effect of Povidone-iodine 0.5% as Mouthwash/Gargle on SARS-CoV-2 Load (COVID 19) as an Adjuvant Infection Control Measure in Dental Practice

University of Pennsylvania·interventional·Posted Feb 15, 2022·Updated Aug 14, 2023

In Brief

A Phase 2 clinical trial evaluating Mouth rinse for COVID-19. Completed, enrolled 40 participants across 1 site.

Detailed Summary

This study is a two-arm, randomized, 2-phase study. Phase I will be double blinded clinical trial of the safety and efficacy of an antiseptic mouthwash solution on reducing SARS-CoV-2 load in COVID 19+ adult individuals. Phase II is designed as an open label trial, and all subjects will receive the active mouthwash.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCOVID-19
CountriesUnited States
CollaboratorsAvrio Health

Timeline

Phase 2CompletedFinished
20222023202420252026
First PostedFeb 15, 2022
Enrollment StartFeb 7, 2022
Primary CompletionJul 7, 2022
Study CompletionJul 13, 2022
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 4.4 years ago

Interventions

Mouth rinsedrug

Subjects will be asked to rinse/gargle one time with 10 mL of assigned mouth rinse for 30 seconds.