CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 276 enrolled / 276 target
Drug / intervention
Photon-counting detector computed tomography (PCD-CT)other
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05240807
NCT05240807N/ACompletedHigh Momentum (6.0/mo)Completion was 4mo ago

Comprehensive Characterization of Coronary Atherosclerotic Disease Using Photon-counting Detector Dual-source CT and Its Impact on Patient Management

Mayo Clinic·interventional·Posted Feb 15, 2022·Updated Jun 12, 2026

In Brief

A clinical study evaluating Photon-counting detector computed tomography (PCD-CT) for Coronary Artery Disease. Completed, enrolled 276 participants across 1 site.

Signals

Enrolling ahead of pace

Detailed Summary

The purpose of this research trial is to determine whether images taken using a Photon Counting Detector CT scanner (PCD-CT) provide clinically important information about the severity of suspected coronary artery disease and perfusion defects compared to traditional Energy Integrating Detector CT (EID-CT) and nuclear medicine cardiac stress tests.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2023202420252026
First PostedFeb 15, 2022
Enrollment StartAug 24, 2022
Primary CompletionFeb 19, 2026
Study CompletionMar 19, 2026
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 4.4 years ago

Arms & Interventions

Clinical Coronary CTA Cohortexperimental

Subjects scheduled for a clinically indicated coronary CT angiogram will receive a research contrast-enhanced coronary CT angiogram using photon-counting detector CT.

Diagnostic Test: Photon-counting detector computed tomography (PCD-CT)
Clinical Nuclear Medicine or MRI Cardiac Stress Test Cohortexperimental

Subjects scheduled for a clinically indicated nuclear medicine or MRI cardiac stress test will receive a research contrast-enhanced coronary CT angiogram using photon-counting detector CT at rest and after administration of a cardiac stress agent.

Diagnostic Test: Photon-counting detector computed tomography (PCD-CT)

Interventions

Photon-counting detector computed tomography (PCD-CT)other

Cardiac CT imaging will be performed using a newly developed CT scanner that uses photon-counting detectors and the results compared to those from conventional CT, MRI, or nuclear medicine imaging systems