CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 120 enrolled
Drug / intervention
3% PVM/MA + 5% KNO3 Combination +3 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05243745
NCT05243745N/ACompleted
CompareCT.gov

An 8-week, Randomised, Controlled, Examiner-Blind, Proof of Principle Study Investigating the Ability of a 3% Methyl Vinyl Ether/Maleic Anhydride Co-Polymer (PVM/MA) + 5% Potassium Nitrate (KNO3) Combination Toothpaste to Protect From Dentine Hypersensitivity

HALEON·interventional·Posted Feb 17, 2022·Updated Sep 20, 2024

In Brief

A clinical study evaluating 3% PVM/MA + 5% KNO3 Combination, 3% PVM/MA only, and 2 other interventions for Dentin Sensitivity. Completed, enrolled 120 participants across 1 site.

Detailed Summary

This proof of principle (PoP) study will evaluate the ability of an experimental combination toothpaste formulation to protect sensitive teeth from dentine hypersensitivity.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDentin Sensitivity
CountriesUnited Kingdom
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedFeb 17, 2022
Enrollment StartFeb 28, 2022
Primary CompletionOct 3, 2022
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 4.4 years ago

Interventions

3% PVM/MA + 5% KNO3 Combinationother

Toothpaste containing 3% PVM/MA + 5% KNO3 as combination will be used as test product.

3% PVM/MA onlyother

Toothpaste containing 3% PVM/MA only will be used as comparator 1 product.

5% KNO3 Onlyother

Toothpastes containing 5% KNO3 only will be used as comparator 2 product.

Regular Fluorideother

Toothpaste containing regular fluoride will be used as negative control.