CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 66 enrolled
Drug / intervention
Fentanyl/Hydromorphone +1 moredrug
Likely dose
Methadone 0.1mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05244226
NCT05244226Phase 2Completed

Pediatric Pain Optimization After Tonsillectomy: A Randomized Double Blind Methadone Pilot Study

Duke University·interventional·Posted Feb 17, 2022·Updated Oct 17, 2024

In Brief

A Phase 2 clinical trial evaluating Fentanyl/Hydromorphone and Methadone for Obstructive Sleep Apnea and 2 related conditions. Completed, enrolled 66 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedFeb 17, 2022
Enrollment StartApr 8, 2022
Primary CompletionMay 10, 2023
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 4.4 years ago

Interventions

Fentanyl/Hydromorphonedrug

Per routine care

Methadonedrug

Initial dosing 0.1mg/kg, potential to escalate to 0.15mg/kg following interim analysis