CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 88 enrolled
Drug / intervention
Palmidrol +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05246670
NCT05246670Phase 2Active

Treatment of Established Chemotherapy-Induced Neuropathy With N-Palmitoylethanolamide, a Cannabimimetic Nutraceutical: A Randomized Double-Blind Phase II Pilot Trial

Academic and Community Cancer Research United·interventional·Posted Feb 18, 2022·Updated Sep 22, 2025

In Brief

A Phase 2 clinical trial evaluating Palmidrol, Placebo Administration, and 1 other intervention for Chemotherapy-Induced Peripheral Neuropathy and 2 related conditions. Active but no longer recruiting, targeting 88 participants across 10 sites.

Detailed Summary

This phase II trial tests whether PEA works to relieve the symptoms of chemotherapy-induced peripheral neuropathy in patients with cancer. Chemotherapy-induced peripheral neuropathy refers to a nerve problem that causes pain, numbness, tingling, or muscle weakness in different parts of the body, and is caused by chemotherapy. PEA may be useful against bothersome nerve symptoms.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2ActiveOverdue
2023202420252026
First PostedFeb 18, 2022
Enrollment StartMay 16, 2022
Primary CompletionFeb 12, 2024
Study CompletionFeb 28, 2026
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 4.4 years ago

Interventions

Palmidroldrug

Given PEA PO

Placebo Administrationdrug

Given PO

Quality-of-Life Assessmentother

Ancillary studies