At a glance
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Pretreatment With Unfractionated Heparin for ST Elevation Myocardial Infarction
In Brief
A Phase 4 clinical trial evaluating Unfractionated heparin for STEMI - ST Elevation Myocardial Infarction. Completed, enrolled 600 participants across 1 site.
Detailed Summary
Rupture of a coronary artery plaque leads to thrombotic occlusion of the coronary artery and would present as ST segment elevation myocardial infarction. Early treatment with aspirin and early primary percutaneous coronary intervention are indicated. Anticoagulation therapy, usually with unfractionated heparin, is required during percutaneous coronary intervention. Investigators hypothesis is that pretreatment with unfractionated heparin in addition to aspirin at first medical contact may facilitate spontaneous reperfusion of culprit artery and procedural thrombotic complication in patients with ST elevation myocardial infarction without significant risk of bleeding complications.
Study Details
Timeline
Interventions
Unfractionated heparin at dose of 100 IU /kg body weight