CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 258 enrolled
Drug / intervention
routine postoperative calcium and calcitriol +1 moredrug
Likely dose
routine postoperative calcium and calcitriol 1,200 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05252884
NCT05252884N/ACompleted
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Comparison of Routine Prophylactic Calcium + Calcitriol and Selective Use Based on PTH for the Prevention of Postoperative Hypocalcemia in Patients With Total Thyroidectomy. Randomized Clinical Trial

Centro de Excelencia en Enfermedades de Cabeza y Cuello·interventional·Posted Feb 23, 2022·Updated Feb 7, 2025

In Brief

A clinical study evaluating calcium correction according to PTH levels and routine postoperative calcium and calcitriol for Thyroid Cancer and 3 related conditions. Completed, enrolled 258 participants across 2 sites.

Detailed Summary

The objective of this study is to compare the frequency of post-thyroidectomy symptomatic and biochemical hypocalcaemia between the strategy of routine prophylactic calcium + calcitriol vs the administration of calcium guided by PTH values.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsThyroid Cancer, Goiter, Thyroiditis, Hyperthyroidism
CountriesColombia
CollaboratorsIPS universitaria, Hospital San Vicente Fundación, Clinica Las Vegas- Grupo QuironSalud

Timeline

N/ACompletedFinished
2023202420252026
First PostedFeb 23, 2022
Enrollment StartJun 30, 2022
Primary CompletionOct 30, 2024
Study CompletionDec 20, 2024
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 4.4 years ago

Interventions

calcium correction according to PTH levelsother

A PTH blood test will be performed 4 hours post-thyroidectomy. If the PTH result is \>15 pg/mL, the patient will be discharged without calcium intake; if PTH \< 15 pg/mL, start a dose of 1200 mg Calcium carbonate every 8 hours + 0.25 mcg of calcitriol every 12 hours orally for 15 days

routine postoperative calcium and calcitrioldrug

The patient will receive a dose of 1,200 mg Calcium carbonate every 8 hours + 0.25 mcg of calcitriol every 12 hours orally for 15 days, starting on the same day as the intervention.