CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
Metyrapone Capsulesdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05255900
NCT05255900N/ACompleted

Metabolic, Pressor and Neuropsychological Effects of Metyrapone Treatment in Patients With Hypercortisolism

Istituto Auxologico Italiano·observational·Posted Feb 25, 2022·Updated Mar 30, 2026

In Brief

An observational study evaluating Metyrapone Capsules for Hypercortisolism. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The aims of the present study are to evaluate in patients with mild hypercortisolism the effect of metyrapone treatment on glycometabolic control, blood pressure, thrombotic risk parameters, lipid profile, bone turnover markers, mental health and cortisol circadian rhythm.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesItaly
CollaboratorsHRA Pharma

Timeline

N/ACompletedFinished
2023202420252026
First PostedFeb 25, 2022
Enrollment StartApr 28, 2022
Primary CompletionJun 30, 2025
Study CompletionDec 31, 2025
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 4.4 years ago

Interventions

Metyrapone Capsulesdrug

Exposure to 24 weeks of treatment with metyrapone