CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 50 enrolled
Drug / intervention
Time-restricted eating +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05256888
NCT05256888N/AActive

Time-Restricted Eating to Address Persistent Cancer-Related Fatigue: The Fatigue REDuction After Cancer (FREDA) Trial

University of Maryland, Baltimore·interventional·Posted Feb 25, 2022·Updated May 7, 2025

In Brief

A clinical study evaluating Time-restricted eating and Healthy lifestyle education for Neoplasms and 6 related conditions. Active but no longer recruiting, targeting 50 participants across 1 site.

Detailed Summary

This study will assess the feasibility of delivering a 12-week time-restricted eating intervention as well as the intervention's preliminary efficacy on persistent cancer-related fatigue among cancer survivors compared to a general health education control. Participants will be randomized 1:1 to one of two arms: time-restricted eating or control. Those in the intervention arm will self-select a 10-hour eating window in which to consume all food and beverages (water is allowed any time, black coffee and unsweetened tea are allowed in the morning). Both groups will receive weekly educational tips on healthy lifestyle behaviors in cancer survivorship. This study will also explore relationships between fatigue, circadian rhythm, and glucose metabolism. The hypothesis is that recruitment will be feasible, and participants will adhere to time-restricted eating and complete study activities over the course of the 12 weeks. The second hypothesis is that time-restricted eating will lead to less fatigue at 12 weeks compared to the control, accounting for baseline fatigue levels.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/AActiveOverdue
2023202420252026
First PostedFeb 25, 2022
Enrollment StartJan 26, 2023
Primary CompletionJun 1, 2024
Study CompletionApr 1, 2026
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 4.4 years ago

Interventions

Time-restricted eatingbehavioral

12 weeks of time-restricted eating (10-hour window)

Healthy lifestyle educationbehavioral

Weekly tips on healthy lifestyle behaviors (e.g., diet, exercise, sleep) for 12 weeks