CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 28 enrolled
Drug / intervention
SENS-401 (R-Azasetron Besylate)drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05258773
NCT05258773Phase 2Completed

A Phase IIa, Multicenter, Randomized, Controlled, Open-label Study to Evaluate the Presence of SENS-401 in the Perilymph After 7 Days of Repeated Oral Administration in Adult Participants Scheduled for Cochlear Implantation

Sensorion·interventional·Posted Feb 28, 2022·Updated Apr 23, 2025

In Brief

A Phase 2 clinical trial evaluating SENS-401 (R-Azasetron Besylate) for Hearing Loss. Completed, enrolled 28 participants across 7 sites in 2 countries.

Detailed Summary

The aim of this study is to detect the presence of SENS-401 in the perilymph of participants undergoing cochlear implant surgery after 7 days of oral administration of SENS-401.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHearing Loss
CountriesAustralia, France
Collaborators--

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedFeb 28, 2022
Enrollment StartAug 10, 2022
Primary CompletionDec 18, 2023
Study CompletionMay 31, 2024
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 4.3 years ago

Interventions

SENS-401 (R-Azasetron Besylate)drug

Patients will receive SENS-401 ((R)-azasetron besylate) for 7 days B.I.D. before cochlear implant surgery and during 6 weeks after the surgery.