CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 596 enrolled
Drug / intervention
ileusother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05262569
NCT05262569N/ACompleted

Increased Postoperative Opioid Use is a Risk Factor for an Ileus After Laparoscopic Colorectal Surgery---A Case Control Study

Peking University People's Hospital·observational·Posted Mar 2, 2022·Updated Aug 9, 2022

In Brief

An observational study evaluating ileus for Ileus and Opioid Use. Completed, enrolled 596 participants across 1 site.

Detailed Summary

Postoperative ileus (POI) is a significant complication after colorectal surgery, with reported incidence ranging from 10\~30%, leading to increased morbidity, hospital length of stay, and thus medical cost. To determine the risk factors for POI is one of the key elements for Enhanced Recovery after Surgery protocol. Increased perioperative opioid usage has been proposed as an independent risk factor for postoperative ileus, as perioperative opioid minimization has proposed to be an effective measure to decrease the incidence of POI. Although opioids are widely used to attenuate stress during surgery, and represent the cornerstone of pain treatment, anesthesiologists are strive to minimize opioid use to decrease opioid-related GI side effects. In this study, the investigators aim to find out the general occurrence of POI in the laparoscopic colorectal surgery and the effects of the postoperative opioid usage on this outcome. The strategies of opioid minimization was also investigated.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsIleus, Opioid Use
CountriesChina
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedMar 2, 2022
Enrollment StartApr 1, 2022
Primary CompletionMay 31, 2022
Study CompletionJun 30, 2022
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 4.3 years ago

Interventions

ileusother

retrospectively allocation according to a postoperative outcome-ileus