CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled
Drug / intervention
3-hydroxybutyratedietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

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Search/NCT05263401
NCT05263401N/ACompleted
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3-hydroxybutyrate as a Meal Primer in Patients With Type 2 Diabetes

University of Aarhus·interventional·Posted Mar 2, 2022·Updated Apr 4, 2023

In Brief

A clinical study evaluating 3-hydroxybutyrate for Type 2 Diabetes and Ketoses, Metabolic. Completed, enrolled 14 participants across 1 site.

Detailed Summary

The main objective of this clinical trial is to study the effects of orally administered ketone drinks containing the ketone body, 3-hydroxybutyrate (3-OHB), just before a meal in patients with type 2 diabetes. Moreover the investigators will compare the effects of two different ketone drinks. The hypothesis is: 3-OHB as a pre-meal may: * Lower postprandial blood glucose and lipids. * Mediate release of intestinal hormones and affect gastric emptying. * Affect appetite and other subjective measures related to food intake. The effects of 3-OHB as a pre-meal will be investigated by blood samples, isotopic tracers examinations, paracetamol test, questionnaires and meal test.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 2 Diabetes, Ketoses, Metabolic
CountriesDenmark
CollaboratorsAarhus University Hospital

Timeline

N/ACompletedFinished
20222023202420252026
First PostedMar 2, 2022
Enrollment StartJan 1, 2022
Primary CompletionSep 30, 2022
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 4.3 years ago

Interventions

3-hydroxybutyratedietary

Orally administered pre-meal drinks.