CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 3,346 enrolled
Drug / intervention
nirmatrelvir / ritonavirdrug
Likely dose
Nirmatrelvir 300 mg / ritonavir 100 mg orally twice daily for 5 daysAI-extracted
Key inclusion· 2
  • Receiving PAXLOVID (nirmatrelvir/ritonavir)
  • No prior history of PAXLOVID use
Key exclusion· 0

None specified.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05263908
NCT05263908N/ACompleted

General Investigation for PAXLOVID PAC

Pfizer·observational·Posted Mar 3, 2022·Updated Sep 3, 2025

In Brief

An observational study evaluating nirmatrelvir / ritonavir for SARS-CoV-2 Infection. Completed, enrolled 3,346 participants across 1 site.

Detailed Summary

The purpose of this post marketing observational study is to learn about the safety and effects of the commercial medicine (called PAXLOVID) for the treatment of COVID-19. This study is intended to be registered with the participants who: * Have taken PAXLOVID PACK and have no history of using this medicine. * Are 12 years and older All participants will receive PAXLOVID, a standard treatment for COVID-19. Participants will take PAXLOVID 2 times a day by mouth or as prescribed. We will examine the experiences of people taking PAXLOVID. This will help us determine if PAXLOVID is safe and effective. Participants will be followed up for 28 days after taking PAXLOVID. During this time, participants will be closely watched for the safety and effects of PAXLOVID.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesJapan
Collaborators--

Timeline

N/ACompletedFinished
2023202420252026
First PostedMar 3, 2022
Enrollment StartMar 31, 2022
Primary CompletionJul 10, 2023
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 4.3 years ago

Interventions

nirmatrelvir / ritonavirdrug

The usual dosage in adults and pediatric patients (≥12 years of age weighing ≥40 kg) is 300 mg of Nirmatrelvir and 100 mg of ritonavir all taken together orally twice daily for 5 days.