CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
Bone augmentation with minimally invasive corticotomy (piezotomy) +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05264480
NCT05264480N/ACompleted
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A Novel Periodontally Accelerated Osteogenic Orthodontics (PAOO) in the Prevention of Buccal Bone Dehiscence in Patients Receiving Orthodontic Therapy- a Randomized Controlled Clinical Trial

Semmelweis University·interventional·Posted Mar 3, 2022·Updated Apr 28, 2026

In Brief

A clinical study evaluating Bone augmentation with minimally invasive corticotomy (piezotomy) and Bone augmentation without corticotomy for Bone Loss and Tooth Movement. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The aim of this study is to evaluate in a prospective, randomized, controlled clinical trail the effectiveness of preorthodontic piezotomy combined with a buccal bone augmentation (in other name periodontlly accelerated osteogenic orthodontics: PAOO)in the prevention of gingival recession, and in the acceleration of orthodontic tooth movement (OTM).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBone Loss, Tooth Movement
CountriesHungary
CollaboratorsNSK Europe GmbH

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedMar 3, 2022
Enrollment StartApr 1, 2019
Primary CompletionJan 30, 2024
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 4.3 years ago

Interventions

Bone augmentation with minimally invasive corticotomy (piezotomy)procedure

Double layer tunnel flap preparation. Subperiosteally "sticky bone" containing platelet rich fibrin (PRF) and xenograft is utilized for bone augmentation, while supraperiosteally PRF membranes are used for soft tissue augmentation. Trough the vertical releasing incisions a piezosurgical device is used to perform corticotomy. 1 week after surgery OTM is initiated.

Bone augmentation without corticotomyprocedure

Double layer tunnel flap preparation. Subperiosteally "sticky bone" containing platelet rich fibrin (PRF) and xenograft is utilized for bone augmentation, while supraperiosteally PRF membranes are used for soft tissue augmentation. Corticotomy is not performed in this group. 1 week after surgery OTM is initiated.