CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 53 enrolled
Drug / intervention
Ociperlimab +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05267054
NCT05267054Phase 2Completed

A Phase 1b/2 Study Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of Ociperlimab (BGB-A1217) in Combination With Tislelizumab (BGB-A317) or Rituximab in Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma

BeiGene·interventional·Posted Mar 4, 2022·Updated Sep 15, 2025

In Brief

A Phase 2 clinical trial evaluating Ociperlimab, Tislelizumab, and 1 other intervention for Relapsed Diffuse Large B-cell Lymphoma and Refractory Diffuse Large B-cell Lymphoma. Completed, enrolled 53 participants across 19 sites.

Detailed Summary

The primary purpose of this study is to assess the safety and tolerability of ociperlimab (BGB-A1217) in combination with tislelizumab (BGB-A317) or rituximab in participants with relapsed or refractory (R/R) diffuse large B cell lymphoma (DLBCL)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 2CompletedFinished
2023202420252026
First PostedMar 4, 2022
Enrollment StartApr 25, 2022
Primary CompletionAug 30, 2024
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 4.3 years ago

Interventions

Ociperlimabdrug

administered intravenously

Tislelizumabdrug

Administered intravenously once every 3 weeks

Rituximabdrug

Administered intravenously once every 3 weeks