CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 195 enrolled
Drug / intervention
MRIother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05270356
NCT05270356N/ACompleted
CompareCT.gov

MINDS Imaging Ancillary Study

University of Pittsburgh·observational·Posted Mar 8, 2022·Updated Oct 31, 2025

In Brief

An observational study evaluating MRI for Adult Congenital Heart Disease. Completed, enrolled 195 participants across 13 sites in 2 countries.

Detailed Summary

This study is an ancillary study to the NHLBI-funded Pediatric Heart Network (PHN) "Multi-Institutional Neurocognitive Discovery Study" (MINDS) in Adult Congenital Heart Disease (ACHD). The MINDS-ACHD" study will recruit 500 complex CHD patients between18-30 years old. The investigators propose to quantitate multi-modal neuroimaging biomarkers (brain injury, structure and physiology) which are not only important components of brain and cognitive reserve but can be predictive of neurocognitive decline and early onset of dementia in the aging non-CHD population.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsAdult Congenital Heart Disease
CountriesCanada, United States
CollaboratorsBoston Children's Hospital, National Heart, Lung, and Blood Institute (NHLBI)

Timeline

N/ACompletedFinished
20222023202420252026
First PostedMar 8, 2022
Enrollment StartMay 27, 2021
Primary CompletionMay 31, 2025
TodayJul 2, 2026
Enrollment to primary: 4.0 yearsPosted 4.3 years ago

Interventions

MRIother

Magnet Resonance Imaging of the Brain without Contrast