CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 151 enrolled
Drug / intervention
BXCL501 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05271552
NCT05271552Phase 3Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Efficacy And Safety Study of PRN Dosing of BXCL501 Over A 12 Week Period In Subjects With Agitation Associated With Dementia

BioXcel Therapeutics Inc·interventional·Posted Mar 9, 2022·Updated Dec 31, 2025

In Brief

A Phase 3 clinical trial evaluating BXCL501 and Matching Placebo for Agitation and Dementia. Completed, enrolled 151 participants across 11 sites.

Detailed Summary

A study to determine the safety and efficacy of BXCL501 dosing for episodes of agitation associated with dementia when they occur (given as needed \[PRN\]), for a maximum of 28 doses within a 12-week treatment period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAgitation, Dementia
CountriesUnited States

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedMar 9, 2022
Enrollment StartApr 27, 2022
Primary CompletionApr 21, 2023
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 4.3 years ago

Interventions

BXCL501drug

Sublingual Film

Matching Placebodrug

Sublingual Placebo Film