CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 986 enrolled
Drug / intervention
Insulin Efsitora Alfa +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05275400
NCT05275400Phase 3Completed

A Phase 3, Multicenter, Randomized, Parallel-Design, Open-Label Trial to Evaluate the Efficacy and Safety of LY3209590 Compared With Insulin Degludec in Participants With Type 2 Diabetes Currently Treated With Basal Insulin (QWINT-3)

Eli Lilly and Company·interventional·Posted Mar 11, 2022·Updated Jun 3, 2025

In Brief

A Phase 3 clinical trial evaluating Insulin Efsitora Alfa and Insulin Degludec for Type 2 Diabetes. Completed, enrolled 986 participants across 127 sites in 10 countries.

Detailed Summary

The reason for this study is to see if the study drug insulin efsitora alfa (LY3209590) is safe and effective in participants with Type 2 diabetes that have already been treated with basal insulin. The study consists of a 3-week screening/lead-in period, a 78-week treatment period and a 5-week safety follow-up period. The study will last up to 86 weeks.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 2 Diabetes
CountriesArgentina, Hungary, Japan, Poland, Puerto Rico, Slovakia, South Korea, Spain, Taiwan, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2023202420252026
First PostedMar 11, 2022
Enrollment StartMar 8, 2022
Primary CompletionMay 15, 2024
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 4.3 years ago

Interventions

Insulin Efsitora Alfadrug

Administered SC

Insulin Degludecdrug

Administered SC