CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 53 enrolled
Drug / intervention
Dual-energy X-ray absorptiometry +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05283148
NCT05283148N/AActive

Association Between Low Bone Density, Vertebral Fractures, and Pain in Sickle Cell Disease

University of California, Davis·interventional·Posted Mar 16, 2022·Updated Aug 24, 2025

In Brief

A clinical study evaluating Dual-energy X-ray absorptiometry, Vertebral fracture analysis, and 1 other intervention for Sickle Cell Disease and 9 related conditions. Active but no longer recruiting, targeting 53 participants across 1 site.

Detailed Summary

A prospective study to determine how low bone mineral density and/or vertebral compression fractures associate with pain in adults with sickle cell disease

Study Details

Timeline

N/AActive
2023202420252026
First PostedMar 16, 2022
Enrollment StartNov 3, 2022
Primary CompletionApr 30, 2024
Study CompletionJul 31, 2026
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 4.3 years ago

Interventions

Dual-energy X-ray absorptiometryother

Measure bone mineral density at the lumbar spine, left total hip, left forearm, and whole body

Vertebral fracture analysisother

Obtain thoracolumbar morphometry in DXA scan, then determine presence and severity of vertebral compression fractures by VFA

Adult Sickle Cell Quality of Life Measurement System pain impact questionnaireother

Calculate patient-reported total pain scores to determine the pain phenotype of each study participant