CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 168 enrolled
Drug / intervention
Vaxelis™biological
Likely dose
Vaxelis™ 0.5 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05289271
NCT05289271Phase 4Completed

A Phase 4, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, and Immunogenicity of Vaxelis™ in Healthy Children Previously Vaccinated With a 2-Dose Primary Infant Series of Either Vaxelis™ or Hexyon™

Merck Sharp & Dohme LLC·interventional·Posted Mar 21, 2022·Updated Jul 29, 2024

In Brief

A Phase 4 clinical trial evaluating Vaxelis™ for Vaccines, Combined and Hexavalent Vaccine. Completed, enrolled 168 participants across 13 sites in 3 countries.

Detailed Summary

The primary objectives of this study are to evaluate the safety, tolerability, and immunogenicity of a booster dose of Vaxelis™ (V419) given at \~11 to 13 months of age in healthy participants who were previously vaccinated with a 2-dose primary infant series of either Vaxelis™ or Hexyon™.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany, Italy, Spain
Collaborators--

Timeline

Phase 4CompletedFinished
2023202420252026
First PostedMar 21, 2022
Enrollment StartMar 25, 2022
Primary CompletionAug 30, 2022
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 4.3 years ago

Interventions

Vaxelis™biological

Vaxelis™ 0.5 mL sterile suspension in prefilled syringe for intramuscular administration.