At a glance
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Neuromodulation of Affective Valence in Humans by Amygdala Stimulation
In Brief
A clinical study evaluating Electrical Stimulation for Refractory Epilepsy. Completed, enrolled 16 participants across 1 site.
Detailed Summary
This study will enroll patients with epilepsy who are being evaluated for epilepsy surgery and have intracranial EEG electrodes. In this study, the aim is to record brain signals from areas important in social and emotional processing and to understand how electrical brain stimulation - called neuromodulation - affects such processing. Patients enrolled in this study will be asked to view images depicting a variety of emotionally positive, negative, or neutral themes. As the patient views these images, a small amount of imperceptible and painless electric current will be used to map function of certain parts of a human brain. The overarching goal of the study is to determine if neuromodulation can be used in certain areas of the brain to treat cognitive disorders such as memory loss and post-traumatic stress disorder.
Study Details
Timeline
Interventions
We will use a computer randomized stimulation of specific areas in the amygdala while showing a computer randomized set of pictures.