CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 48 enrolled
Drug / intervention
UC-MSC infusion via intravenous route +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT05292625
NCT05292625Phase 2Completed

Outcomes of Umbilical Cord -derived Mesenchymal Stem Cell Infusion in Patients with Neurological Sequelae After Ischemic Stroke

Vinmec Research Institute of Stem Cell and Gene Technology·interventional·Posted Mar 23, 2022·Updated Jan 6, 2025

In Brief

A Phase 2 clinical trial evaluating UC-MSC infusion via intravenous route, UC-MSC infusion via intrathecal route, and 1 other intervention for Ischemic Stroke. Completed, enrolled 48 participants across 1 site.

Detailed Summary

This trial is to investigate the safety and potential therapeutic efficacy of allogeneic administration of umbilical cord-derived MSCs (UC-MSCs) in combination with standard neurological complications after ischemic stroke treatment in Vietnam.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIschemic Stroke
CountriesVietnam
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedMar 23, 2022
Enrollment StartJul 7, 2020
Primary CompletionDec 30, 2022
Study CompletionNov 30, 2023
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 4.3 years ago

Interventions

UC-MSC infusion via intravenous routebiological

Patients assigned to UC-MSC administration groups will receive two administrations at a dose of 1.5 million cells/kg patient body weight via the intravenous (IV) route with a 3-month intervening interval

UC-MSC infusion via intrathecal routebiological

Patients assigned to UC-MSC administration groups will receive two administrations at a dose of 1.5 million cells/kg patient body weight via the intrathecal route with a 3-month intervening interval

standard stroke treatment and rehabilitation therapyother

Each patient can receive up to 30 days of rehabilitation therapy